Integrative eQTL–Single-Cell Analysis
Select a dataset, review MR evidence, and inspect gene-level single-cell atlas views.
Dataset Catalog
Available MR result sets
The selected dataset stays highlighted here and syncs with the MR Dataset control in the left query builder.
Result Review
Review the ranked MR table, then open a gene.
MR Table
Current filtered records
Each row treats a gene expression feature as the exposure and the selected neuroendocrine neoplasms endpoint as the outcome. The table keeps the gene, method, effect estimate, uncertainty interval, significance values, instrument count, and NENs cancer type together for review before opening gene-level single-cell evidence.
Sensitivity analyses follow the number of instruments: records with one SNP are not tested, two SNPs report heterogeneity only, three SNPs report heterogeneity and pleiotropy, and four or more SNPs report the full set. MR-PRESSO global test P values are reported only when nsnp >= 4.
| Gene | Method | Beta | SE | or | or_lci95 | or_uci95 | pval | fdr | heterogeneity_pval | pleiotropy_pval | mrpresso_pval | nsnp | NENs Cancer Type |
|---|
Figure Panel
Interpretation figures for the active MR result set
Double-click any figure to enlarge it. Each card provides both PNG and PDF downloads. The forest plot and heatmap share the same default 12-gene view, while the volcano plot shows Beta against significance and can accent selected targets.
In the sensitivity heatmap, values below 0.05 are shown using a distinct highlight color, whereas values from 0.05 to 1 are mapped to the shared red-to-blue legend scale.
Example: TP53, EGFR, RET
Example: TP53, EGFR, RET
Default sync: forest selection drives this panel
Gene Evidence
Gene board
Context Filters
Atlas Feature Selection Scope
Gene Summary
Literature Evidence
Selected Gene
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Searching literature records...
This lookup uses "Neuroendocrine" plus the selected gene symbol and may miss relevant articles. Please verify manually before interpretation.
Figure Panel
Single-cell evidence views for the active gene
Double-click any figure to enlarge it. Each card provides both PNG and PDF downloads.
Status Comparison follows the current organ and celltype filters only, and defaults to no additional filtering.
AI Overview
AI Result Interpretation
This panel uses the configured AI service to analyze results and answer questions. If AI chat is disabled, use Export AI report to obtain the standardized output and submit it to an LLM.
Click Send to interpret the current analysis result.